Our client is an exciting clinical-stage biotechnology company focused on developing locally delivered, extended-release products that have the potential to address therapeutic areas with high unmet medical need. The Company has developed a proprietary technology designed to facilitate targeted drug delivery of both existing and novel drugs. The technology is designed to support an extended duration of effect and delivery of drugs in a hyper-localized fashion, targeting only the tissues that physicians want to treat.
The Company believes the potential for fewer adverse events may be achieved through the precision targeting and the stable and flat delivery of the active ingredient when using this proprietary technology, versus the peaks and troughs seen with more traditional drug delivery methods. The precision of the platform has the potential to augment and transform existing FDA-approved drugs to improve their safety, tolerability, efficacy and duration of effect. The potential uses in therapeutic areas may go beyond initial targets and also to be applicable in oncology, infectious disease and other critical disease areas.
The current target application is currently in a Phase 1b/2 trial. Potential pipeline indications include candidates for other indications, each designed to improve on the activity and tolerability of currently approved drugs. Our client is looking for people who would like to work for a fast-paced, growing company that fosters a creative spirit and integrated teamwork and who are eligible to work in Canada.
Job Description: Role Summary Analytical Development Scientist is responsible for supporting technical operations related to analytical development and testing of sustained release drug products (polymer drug delivery systems). This includes analytical development, stability studies, data analysis, and documentation to support ongoing and new programs. This is an onsite position in Vancouver, and the scientist is required to perform laboratory development work. Reports to: Associate Director, Analytical Chemistry Key Responsibilities
Support analytical development activities including initial lab assessments, method development, and troubleshooting
Support stability programs including protocol drafting, report writing, and data trending
Prepare and review analytical protocols and reports (validation, development, stability)
Perform data analysis and interpretation to support development and regulatory activities
Support coordination of analytical activities with CDMOs and internal teams
Assist with SOP writing, revisions, and document lifecycle management
Contribute to internal technical reports
Routinely provide updates on analytical activities
Requirements
3–5 years’ experience in pharmaceutical industry
PhD or MSc in Chemistry, Biochemistry, Chemical Engineering, or related field. Candidates with BSc plus relevant work experience will be considered
Experience with analytical techniques such as HPLC (RP, SEC), Rheometer, Particle Size, USP Dissolution systems, thermal analysis, etc.
Experience with analytical method development and validation in pharmaceutical industry
Strong data analysis and technical writing skills
Ability to manage multiple tasks in a fast-paced environment
Familiarity with GMP and basic knowledge of ICH, FDA, and USP guidelines is an asset
Additional Attributes:
Highly self-motivated
Ability to work independently and as part of a team